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Symbol Name ID |
Nfatc2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 MGI:102463 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
enlarged thymus |
thymus hyperplasia |
abnormal thymus involution |
enlarged spleen |
abnormal B cell number |
increased B cell number |
increased T cell number |
increased activated T cell number |
increased lymphocyte cell number |
abnormal spleen germinal center morphology |
abnormal mast cell physiology |
abnormal lymphocyte physiology |
abnormal B cell physiology |
increased IgE level |
increased IgG1 level |
increased immunoglobulin level |
abnormal T cell physiology |
abnormal CD4-positive, alpha-beta T cell physiology |
abnormal T-helper 1 physiology |
abnormal T-helper 2 physiology |
abnormal T cell activation |
abnormal interferon level |
abnormal immune system organ morphology |
abnormal lymph node morphology |
abnormal lymph node B cell domain morphology |
enlarged lymph nodes |
lymph node hyperplasia |
abnormal immune system physiology |
decreased interferon-gamma secretion |
abnormal interleukin secretion |
decreased interleukin-13 secretion |
decreased interleukin-4 secretion |
increased interleukin-4 secretion |
increased interleukin-5 secretion |
decreased tumor necrosis factor secretion |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||
| Nfatc2m1Anu/Nfatc2m1Anu | * | ||||||||||||||||||||||||||||||||||||
| Nfatc2tm1Rao/Nfatc2tm1Rao | |||||||||||||||||||||||||||||||||||||
| Nfatc2tm1Srf/Nfatc2tm1Srf | |||||||||||||||||||||||||||||||||||||
| Gt(ROSA)26Sortm1(Nfatc2*)Rao/Gt(ROSA)26Sor+ Tg(Cd4-cre)1Cwi/0 (conditional) |
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| Gt(ROSA)26Sortm2(Nfatc2*)Rao/Gt(ROSA)26Sor+ Tg(Cd4-cre)1Cwi/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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